A study by scientists in China has found that black soybean hull extract can improve the body's absorption of iron, and eating black beans with skin can improve the symptoms of anemia. At the same time, this study provides a new way for the development of safe and efficient drugs to treat anemia .
This research result comes from the team of Professor Wang Fuwei from the School of Public Health of Zhejiang University. They found that the blood-enhancing effect of the black soybean hull extract is achieved by the action of "Hepcidin" in the human body.
Hepcidin is a regulatory molecule produced by the liver and is a key substance that regulates the body's iron homeostasis and iron metabolism. "Excessive activity of hepcidin will cause the iron content in the blood to drop excessively, which in turn restricts the synthesis of red blood cells, which is one of the causes of anemia." Wang Fuwei said.
Reminiscent of the "five kinds of black food" that Chinese medicine is believed to have blood-enhancing effects, Wang Fuwei's team began to verify the blood-enhancing effects of black sesame seeds, black fungus, black dates, black rice, and black beans one by one.
"After experiments, we found that only black beans have a significant effect on improving anemia." Wang Fuwei introduced that in the experiment at the cellular level in vitro, black bean hull extract can effectively inhibit the activity of hepcidin, while in animal experiments, mice eat and fight One week after the crushed black soybean hulls, the hematopoietic function was significantly improved. During the meal, the number of red blood cells, hemoglobin and hematocrit of the body increased significantly.
Wang Fuwei believes that the experimental results prove that the black soybean hull extract can promote iron mobilization in the small intestine, liver, and spleen by inhibiting hepcidin, significantly increase the body's serum iron level, and promote the body's hematopoietic function.
The related papers of this research were published in the famous international journal of nutrition "British Journal of Nutrition" on January 6. Black beans became the first internationally reported food that can directly inhibit hepcidin.
"British Journal of Nutrition" published a comment that Wang Fuwei's team used dietary foods to suppress the discovery of iron, combined basic research with practical applications, and provided a new concept of target health for the prevention and treatment of iron deficiency and inflammatory anemia.
According to statistics, about 2 billion people in the world suffer from anemia. The prevalence of anemia in China is about 15%. The anemia rate of middle-aged and elderly women in rural China is as high as 40%. Wang Fuwei said that the current treatment of anemia mainly depends on iron supplementation with drugs, but this will further strengthen the active level of hepcidin and limit the therapeutic effect. In addition, iron supplementation with drugs will also increase the risk of dementia, and improve the body iron level through dietary intervention Is relatively safe.
"It is natural and effective to eat black beans to nourish the blood. It should be reminded that the skin should not be discarded when eating black beans, because most of the active ingredients are present in the black beans." Wang Fuwei said.
It is understood that the research group is currently conducting in-depth research on the black soybean hull extract, and the related national invention patents applied for have also entered the stage of publicity. The next step will be the drug development of the black soybean hull extract.
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