Britain uses human embryonic stem cells for 3D printing for the first time

According to the physicist organization network report, Heriot-Watt University in the UK has collaborated with a stem cell technology company to develop a valve-based three-dimensional (3D) printing technology. This breakthrough makes it possible to use human embryonic stem cells to "build" human tissues and organs for transplantation. The printed structure can also be used for drug testing to speed up the improvement of the testing process. Related papers were published in the journal "Biomanufacturing" published on February 5.

In recent years, 3D printing methods have gradually developed into the field of bio-manufacturing. Jason King, commercial development manager of Roslyn Serrabo Stem Cell Technology, said: "Usually, cells grown in the laboratory grow in a two-dimensional plane, and only a few cells can be printed in three dimensions. Human stem cells are too sensitive to use this Way to control. We are printing and cultivating human embryonic stem cells for the first time in the world. "

The key issue in the printing process is controllability and injury reduction, so as to ensure the developmental ability and normal function of cells and tissues. Human embryonic stem cells are derived from the "stem cell line" produced in the early stages of the embryo. There is no clear direction of development, and they can differentiate into any type of cell in the human body. The research team developed a vacuum valve-type cell printer. Cells were packed into two separate containers of the printer, and then printed on a single plate in accordance with a pre-programmed program. The printer fully considers the sensitivity and fragility of human embryonic stem cells and can print out highly active cells.

After the human embryonic stem cells are printed, they have to undergo multiple tests, such as testing their activity to see if they can differentiate into different types of cells; testing the printing density, characteristic attributes and distribution of cells to evaluate this The accuracy of the printing method.

"We found that this vacuum valve printing method is very gentle, enough to maintain the developmental ability of stem cells, and it can also accurately shoot the same size sphere. More importantly, the printed human embryonic stem cells maintain their pluripotency, but also Differentiate into other types of cells. "Will Wenmiao Shu, a co-author of the thesis and Heriot-Watt University in the UK, said:" This method uses air pressure to drive the cells, which can be controlled by switching the micro vacuum tube. Changing the nozzle diameter, inlet air pressure or the time to open the vacuum tube can precisely control the number of cells ejected. "

Shu also pointed out that by printing the 3D structure generated by human embryonic stem cells, we can create a more accurate human tissue model, which is very useful for drug development and toxicity testing, because most drug development is aimed at human diseases. It is more meaningful for human organizations to experiment.

Jin said: "This is a scientific advancement. We hope that this advancement will bring long-term great value, provide people with reliable drugs without having to use animals for drug testing, provide organs for transplantation without donation, and be able to Eliminate the problems caused by organ rejection and immunosuppression. "

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Hematite meaning and properties

Hematite is used to improve relationships. If you need your personal relationship to be better, carry a hematite with you always.

The name comes from the Greek word for blood. It has been used as an amulet against bleeding, and so is known as the "blood stone". When arranged like the petals of a flower, it is referred to as the "iron rose". Native American folklore states that war paint made from hematite will make one invincible in battle. People in the eighteenth and nineteenth centuries wore Hematite Jewelry during mourning.

Scientists of the Mars Exploration Rover Project believe that deposits of hematite ono Mars .may help prove whether large amounts of liquid water ever flowed on Mars' surface. They say that where water was, life may have had a chance to thrive as well.

Hematite is good for increasing intuition. In jewelry it is best in a ring worn on the left hand.

Healing properties of Hematite

Hematite stimulates iron absorption in the small intestine, which in turn improves oxygen supply to the body. It can be in direct contact with the skin, but results in inflammation for some people, so test it carefully on yourself before use.

Sources of Hematite

Brazil is the most important source of hematite. Other sources include: China, Canada, England, and Germany.


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